Admission serum potassium level is associated with in-hospital and long-term mortality in ST-elevation myocardial infarctionMahmut Uluganyan1, Ahmet Ekmekçi2, Ahmet Murat2, Şahin Avşar2, Türker Kemal Ulutaş6, Hüseyin Uyarel3, Mehmet Bozbay4, Gökhan Çiçek2, Gürkan Karaca5, Mehmet Eren2
1Clinics Of Cardiology, Kadirli Government Hospital; Osmaniye-turkey
2Clinic Of Cardiology, Dr. Siyami Ersek Thoracic And Cardiovascular Surgery Center Training And Research Hospital; İstanbul-turkey
3Department Of Cardiology, Bezmialem Vakıf University Medical Hospital; İstanbul-turkey
4Department Of Cardiology, Marmara University Hospital; İstanbul-turkey
5Clinic Of Cardiology, Osmancık Government Hospital; Çorum-turkey
6Biochemistry, Kadirli Government Hospital; Osmaniye-turkey
Objective: Current guidelines recommend a serum potassium (sK) level of 4.0-5.0 mmol/L in acute myocardial infarction patients. Recent trials have demonstrated an increased mortality rate with an sK level of >4.5 mmol/L. The aim of this study was to figure out the relation between admission sK level and in-hospital and long-term mortality and ventricular arrhythmias.Keywords: potassium, mortality, myocardial infarction, ventricular arrhythmia, hypokalemia
Methods: Retrospectively, 611 patients with ST-elevation myocardial infarction (STEMI) who underwent primary percutaneous coronary intervention were recruited. Admission sK levels were categorized accordingly: <3.5, 3.5-<4, 4-<4.5, 4.5-<5, and ≥5 mmol/L.
Results: The lowest in-hospital and long-term mortality occurred in patients with sK levels of 3.5 to <4 mmol/L. The long-term mortality risk increased for admission sK levels of >4.5 mmol/L [odds ratio (OR), 1.58; 95% confidence interval (CI) 0.425.9 and OR, 2.27; 95% CI 0.44-11.5 for sK levels of 4.5-<5 mmol/L and ≥5 mmol/L, respectively]. At sK levels <3 mmol/L and ≥5 mmol/L, the incidence of ventricular arrhythmias was higher (p=0.019).
Conclusion: Admission sK level of >4.5 mmol/L was associated with increased long-term mortality in STEMI. A significant relation was found between sK level of <3 mmol/L and ≥5 mmol/L and ventricular arrhythmias.
Mahmut Uluganyan, Ahmet Ekmekçi, Ahmet Murat, Şahin Avşar, Türker Kemal Ulutaş, Hüseyin Uyarel, Mehmet Bozbay, Gökhan Çiçek, Gürkan Karaca, Mehmet Eren. Admission serum potassium level is associated with in-hospital and long-term mortality in ST-elevation myocardial infarction. Anatol J Cardiol. 2016; 16(1): 10-15
Sorumlu Yazar: Mahmut Uluganyan, Türkiye