The Anatolian Journal of Cardiology

[Anatol J Cardiol]
Anatol J Cardiol. 2002; 2(4): 323-329

Apoptosis and Cardiovascular Disease

Hakan Kültürsay1, Meral Kayıkçıoğlu2
1Ege Üniversitesi, Tıp Fakültesi, Kardiyoloji Anabilim Dalı, İzmir, Türkiye
2Ege Üniversitesi Tıp Fakültesi Kardiyoloji Anabilim Dalı, İzmir

Apoptosis is defined as a genetically programmed cell death. Apoptotic cell death plays an important role both in heart development and cardiac disease. This review deals with the key features of this process. The modification of possible interactions between extrinsic and intrinsic factors affecting the cell during apoptotic process may be of major interest in preventing the progression of cardiovascular disease. Current issues on the pathogenetic role of apoptosis in heart disease and how these knowledge can be applied in clinical usage is also evaluated in this review.



Hakan Kültürsay, Meral Kayıkçıoğlu. Apoptosis and Cardiovascular Disease. Anatol J Cardiol. 2002; 2(4): 323-329


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